Catalytic Asymmetric Total Synthesis ofent-Hyperforin
نویسندگان
چکیده
منابع مشابه
A catalytic asymmetric total synthesis of (−)-perophoramidine
We report a catalytic asymmetric total synthesis of the ascidian natural product perophoramidine. The synthesis employs a molybdenum-catalyzed asymmetric allylic alkylation of an oxindole nucleophile and a monosubstituted allylic electrophile as a key asymmetric step. The enantioenriched oxindole product from this transformation contains vicinal quaternary and tertiary stereocenters, and is obt...
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Course objectives: At the end of this course you should be able to: • Recognise the types of functional groups which can be prepared by catalytic asymmetric methods discussed in the course; • Use this knowledge in planning the synthesis of enantiomerically enriched compounds from given prochiral starting materials; • Outline the scope and limitations of any methods you propose, with respect to ...
متن کاملCatalytic asymmetric synthesis
Three researchers share this years’ Nobel Prize in Chemistry; Dr William S. Knowles, who has been working at Monsanto Company, St Louis, USA; Professor Ryoji Noyori, Nagoya University, Chikusa, Nagoya, Japan and Professor K. Barry Sharpless, The Scripps Research Institute, La Jolla, California, USA. The Royal Swedish Academy of Sciences rewards the three chemists for: ”their development of cata...
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2010
ISSN: 1433-7851,1521-3773
DOI: 10.1002/anie.200906678